{"id":9834,"date":"2026-02-24T15:11:44","date_gmt":"2026-02-24T07:11:44","guid":{"rendered":"https:\/\/www.packqc.com\/standard\/iso-719-2\/"},"modified":"2026-04-16T09:54:21","modified_gmt":"2026-04-16T01:54:21","slug":"iso-719","status":"publish","type":"standard","link":"https:\/\/www.packqc.com\/nn\/standard\/iso-719\/","title":{"rendered":"ISO 719"},"content":{"rendered":"<h2 class=\"wp-block-heading\">What is ISO 719?<\/h2>\n\n\n\n<p><strong data-start=\"1071\" data-end=\"1087\">ISO 719:2020<\/strong> is the international standard titled <em data-start=\"1125\" data-end=\"1220\">&#8220;Glass \u2014 Hydrolytic resistance of glass grains at 98 \u00b0C \u2014 Method of test and classification.&#8221;<\/em> It defines a procedure for testing how resistant glass grains are to water at elevated temperatures. The test measures the volume of acid needed to neutralize alkali extracted from a specific mass of glass. Results can be reported either by acid volume or equivalent sodium oxide content, providing a quantifiable basis for classification.<\/p>\n\n\n\n<p>This standard is particularly designed for <strong data-start=\"1605\" data-end=\"1635\">less resistant glass types<\/strong>, such as <strong data-start=\"1645\" data-end=\"1664\">soda-lime glass<\/strong>, unlike <strong data-start=\"1673\" data-end=\"1684\">ISO 720<\/strong>, which targets borosilicate and other more chemically stable glasses.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Hydrolytic Resistance Test for Glass: Why It Matters<\/h2>\n\n\n\n<p>The <strong data-start=\"1824\" data-end=\"1864\">hydrolytic resistance test for glass<\/strong> determines how much alkaline material leaches into water when the glass is exposed to high temperatures. This data is essential for:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Ensuring chemical stability of <strong data-start=\"2032\" data-end=\"2061\">pharmaceutical containers<\/strong> like ampoules, vials, and oral bottles.<\/li>\n\n\n\n<li>Preventing product degradation caused by interaction between packaging and medication.<\/li>\n\n\n\n<li>Classifying glass types based on durability and selecting appropriate packaging materials.<\/li>\n<\/ul>\n\n\n\n<p>A poor hydrolytic resistance rating can indicate a risk of alkali leaching, which may compromise the contents\u2019 shelf life or safety.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Glass Grain Test Procedure Based on ISO 719<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Sample Preparation<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong data-start=\"2601\" data-end=\"2613\">Crushing<\/strong>: Glass articles (annealed) are manually or mechanically crushed into grains.<\/li>\n\n\n\n<li><strong data-start=\"2693\" data-end=\"2704\">Sieving<\/strong>: Grains are separated using sieves of 710 \u00b5m, 500 \u00b5m, and 300 \u00b5m. Only grains passing through 500 \u00b5m but retained on 300 \u00b5m are used.<\/li>\n\n\n\n<li><strong data-start=\"2841\" data-end=\"2853\">Cleaning<\/strong>: Grains are washed with acetone and cleaned in an ultrasonic bath. They are then dried at 140\u00b0C.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Testing Procedure<\/h3>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong data-start=\"2978\" data-end=\"2990\">Weighing<\/strong>: 2 g of clean, dry grains are weighed into each of three volumetric flasks.<\/li>\n\n\n\n<li><strong data-start=\"3069\" data-end=\"3083\">Extraction<\/strong>: The flasks are filled with grade 2 water and heated in a bath to 98\u00b0C for 60 minutes.<\/li>\n\n\n\n<li><strong data-start=\"3173\" data-end=\"3186\">Titration<\/strong>: After cooling, a portion of the supernatant liquid is titrated using methyl red as an indicator to determine the amount of alkali released.<\/li>\n<\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Classification<\/h3>\n\n\n\n<p>Based on the volume of titrant used, the glass is classified into hydrolytic resistance classes. Higher volumes indicate greater alkali release, suggesting lower hydrolytic resistance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Instrument Spotlight: GHR-01A by Cell Instruments<\/h2>\n\n\n\n<p>To streamline the <a href=\"https:\/\/www.iso.org\/standard\/77843.html\" target=\"_blank\" rel=\"noopener nofollow\">ISO 719<\/a> testing process and reduce manual workload, Cell Instruments offers the <strong data-start=\"3695\" data-end=\"3747\">GHR-01A Glass Grain Hydrolytic Resistance Tester<\/strong>. It automates the <strong data-start=\"3766\" data-end=\"3808\">crushing and vibratory sieving process<\/strong>, ensuring repeatable and accurate sample preparation.<br><strong data-start=\"3864\" data-end=\"3881\">Key Features:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong data-start=\"3885\" data-end=\"3919\">Automated Crushing and Sieving<\/strong>: Ensures sample uniformity and compliance with ISO standards.<\/li>\n\n\n\n<li><strong data-start=\"3984\" data-end=\"4007\">HMI Touch Interface<\/strong>: Enhances user control and ease of operation.<\/li>\n\n\n\n<li><strong data-start=\"4056\" data-end=\"4075\">Safety Features<\/strong>: Glass splatter shields and waste collection systems improve lab safety and cleanliness.<\/li>\n\n\n\n<li><strong data-start=\"4167\" data-end=\"4195\">Precision and Efficiency<\/strong>: Automated sieving provides more consistent test samples and minimizes human error.<a href=\"https:\/\/www.packqc.com\/nn\/product\/sale-glass-grain-hydrolytic-resistance-tester\/\"> <\/a><\/li>\n<\/ul>\n\n\n\n<p>The GHR-01A is highly recommended for laboratories and pharmaceutical companies looking to comply with ISO 719 and streamline quality control processes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">\n\t\t\t\tContact Us Get ISO 719 Testing Solution\t\t\t\t<\/h2>\n\n\n\n<p>ISO 719 plays a crucial role in qualifying and classifying glass materials used in pharmaceutical packaging. By following this standard&#8217;s procedures, manufacturers and laboratories can accurately assess <strong data-start=\"5254\" data-end=\"5279\">hydrolytic resistance<\/strong>, improve <strong data-start=\"5289\" data-end=\"5310\">quality assurance<\/strong>, and ensure regulatory compliance. With instruments like Cell Instruments&#8217; <strong data-start=\"5386\" data-end=\"5397\">GHR-01A<\/strong>, the testing process becomes more efficient, safer, and reliable\u2014empowering your lab to maintain the highest standards in product safety and performance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">FAQs<\/h2>\n\n\n\n<p>1. What is the purpose of ISO 719?<br>ISO 719 is used to evaluate the hydrolytic resistance of glass grains at 98\u00b0C, helping classify the chemical durability of glass types, especially soda-lime glass.<\/p>\n\n\n\n<p>2. What types of glass are suitable for testing under ISO 719?<br>The standard applies to less chemically resistant glasses, primarily soda-lime glass. More resistant types like borosilicate glass should be tested using ISO 720.<\/p>\n\n\n\n<p>3. What sample size is required for ISO 719 testing?<br>At least 2 grams of grains per test are needed, with grain sizes between 300 \u00b5m and 500 \u00b5m.<\/p>\n\n\n\n<p>4. How does the GHR-01A improve ISO 719 testing?<br>The GHR-01A automates crushing and sieving processes, improves precision, reduces manual errors, and enhances lab safety and efficiency.<\/p>\n\n\n\n<p>5. What does a high hydrolytic resistance indicate?<br>High resistance means low alkali leaching, indicating that the glass is chemically stable and suitable for pharmaceutical applications.<\/p>","protected":false},"excerpt":{"rendered":"<p>What is ISO 719? ISO 719:2020 is the international standard titled &#8220;Glass \u2014 Hydrolytic resistance of glass grains at 98 \u00b0C \u2014 Method of test and classification.&#8221; It defines a procedure for testing how resistant glass grains are to water at elevated temperatures. The test measures the volume of acid needed to neutralize alkali extracted [&hellip;]<\/p>","protected":false},"featured_media":5519,"parent":0,"template":"","meta":{"_acf_changed":true,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-gradient":""}}},"standard-category":[612],"class_list":["post-9834","standard","type-standard","status-publish","has-post-thumbnail","hentry","standard-category-iso"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.packqc.com\/nn\/wp-json\/wp\/v2\/standard\/9834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.packqc.com\/nn\/wp-json\/wp\/v2\/standard"}],"about":[{"href":"https:\/\/www.packqc.com\/nn\/wp-json\/wp\/v2\/types\/standard"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.packqc.com\/nn\/wp-json\/wp\/v2\/media\/5519"}],"wp:attachment":[{"href":"https:\/\/www.packqc.com\/nn\/wp-json\/wp\/v2\/media?parent=9834"}],"wp:term":[{"taxonomy":"standard-category","embeddable":true,"href":"https:\/\/www.packqc.com\/nn\/wp-json\/wp\/v2\/standard-category?post=9834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}